Protein Engineering and

Biopharmaceutical Sciences Laboratory

蛋白质工程与生物制药实验室

 

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2019

Li J, Zhang L, Xiong J, Cheng X, Huang Y, Su Z, Yi M, Liu S. Polyamines Disrupt the KaiABC Oscillator by Inducing Protein Denaturation.

Gao M, Yang J, Liu S, Su Z, Huang Y. Intrinsically Disordered Transactivation Domains Bind to TAZ1 Domain of CBP via Diverse Mechanisms.

Yang J, Gao M, Xiong J, Su Z, Huang Y. Features of molecular recognition of intrinsically disordered proteins via coupled folding and binding.

Feng C, Huang Y, He W, Cheng X, Liu H, Huang Y, Ma B, Zhang W, Liao C, Wu W, Shao Y, Xu D, Su Z, Lu W. Tanshinones: First-in-Class Inhibitors of the Biogenesis of the Type 3 Secretion System Needle of Pseudomonas aeruginosa for Antibiotic Therapy.

Peng F, Cheng X, Wang H, Song S, Chen T, Li X, He Y, Huang Y, Liu S, Yang F, Su Z. Structure-based reconstruction of a Mycobacterium hypothetical protein into an active Δ5-3-ketosteroid isomerase.

Pi N, Gao M, Cheng X, Liu H, Kuang Z, Yang Z, Yang J, Zhang B, Chen Y, Liu S, Huang Y, Su Z. Recombinant Butelase-Mediated Cyclization of the p53-Binding Domain of the Oncoprotein MdmX-Stabilized Protein Conformation as a Promising Model for Structural Investigation.

Chen Y, Chen X, Yao Z, Shi Y, Xiong J, Zhou J, Su Z, Huang Y. 14-3-3/Tau Interaction and Tau Amyloidogenesis.

Xiong J, Gao M, Zhou J, Liu S, Su Z, Liu Z, Huang Y. The influence of intrinsic folding mechanism of an unfolded protein on the coupled folding-binding process during target recognition.

2018

Jingjing Zhou, Chengbin Qiu, Ni Pi, Sicong Li, Xiyao Cheng, Dr. Lei Zhang, Dr. Yao Chen, Dr. Yongqi Huang, Prof. Dr. Yuhui Sun, Prof. Dr.  Zhengding Su A Protein Biosynthesis Machinery Strategy for Identifying P53PTC‐Rescuing Compounds as Synergic Anti‐Tumor Drugs

Huang Y, Gao M, Su Z. Exploring the Roles of Proline in Three-Dimensional Domain Swapping from Structure Analysis and Molecular Dynamics Simulations.

Gao M, Yang F, Zhang L, Su Z, Huang Y. Exploring the sequence-structure-function relationship for the intrinsically disordered βγ-crystallin Hahellin.

2017

Qin L, Liu H, Chen R, Zhou J, Cheng X, Chen Y, Huang Y, Su Z. Effect of the Flexible Regions of the Oncoprotein Mouse Double Minute X on Inhibitor Binding Affinity.

Gao M, Zhou J, Su Z, Huang Y. Bacterial cupredoxin azurin hijacks cellular signaling networks: Protein-protein interactions and cancer therapy.

Huang Y, Gao M, Yang F, Zhang L, Su Z. Deciphering the promiscuous interactions between intrinsically disordered transactivation domains and the KIX domain.

Chen R, Zhou J, Qin L, Chen Y, Huang Y, Liu H, Su Z. A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors.

2016

Vaughan MD, Su Z, Daub E, Honek JF.  Intriguing cellular processing of a fluorinated amino acid during protein biosynthesis in Escherichia coli.

Ke P, Sun H, Liu M, Su Z, Hu K, Zhua H, Guo H, Sun H, Andresen TL, Olsen LF. Polymeric pH nanosensor with extended measurement range bearing octaarginine as cell penetrating peptide.